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Anabolic steroids are synthetic variations of the male sex hormone testosterone. The proper term for these compounds is anabolic-androgenic steroids . "Anabolic" refers to muscle building, and "androgenic" refers to increased male sex characteristics. Some common names for anabolic steroids are Gear, Juice, Roids, and Stackers.

Health care providers can prescribe steroids to treat hormonal issues, such as delayed puberty. Steroids can also treat diseases that cause muscle loss, such as cancer and AIDS. But some athletes and bodybuilders abuse these drugs to boost performance or improve their physical appearance.

People who abuse anabolic steroids usually take them orally or inject them into the muscles. These doses may be 10 to 100 times higher than doses prescribed to treat medical conditions. Steroids are also applied to the skin as a cream, gel, or patch.

Some athletes and others who abuse steroids believe that they can avoid unwanted side effects or maximize the drugs' effects by taking them in ways that include:

"Anabolic steroids" is the familiar name for synthetic substances related to the male sex hormones (e.g., testosterone). They promote the growth of skeletal muscle (anabolic effects) and the development of male sexual characteristics (androgenic effects) in both males and females. The term "anabolic steroids" will be used throughout this report because of its familiarity, although the proper term for these compounds is "anabolic-androgenic steroids."

Anabolic steroids were developed in the late 1930s primarily to treat hypogonadism, a condition in which the testes do not produce sufficient testosterone for normal growth, development, and sexual functioning. The primary medical uses of these compounds are to treat delayed puberty, some types of impotence, and wasting of the body caused by HIV infection or other diseases.

During the 1930s, scientists discovered that anabolic steroids could facilitate the growth of skeletal muscle in laboratory animals, which led to abuse of the compounds first by bodybuilders and weightlifters and then by athletes in other sports. Steroid abuse has become so widespread in athletics that it can affect the outcome of sports contests.

Illicit steroids are often sold at gyms, competitions, and through mail order operations after being smuggled into this country. Most illegal steroids in the United States are smuggled from countries that do not require a prescription for the purchase of steroids. Steroids are also illegally diverted from U.S. pharmacies or synthesized in clandestine laboratories.

Drugs commonly referred to as steroids can be classified as anabolic (anabolic-androgenic) steroids or corticosteroids. Corticosteroids, such as cortisone or prednisone are drugs that doctors often prescribe to help control inflammation in the body. Corticosteroids are not the same as the anabolic steroids that are often linked with illegal use in sports.

Non-medical use of anabolic steroids is illegal and banned by most major sports organizations. In January 2005, the Anabolic Steroid Control Act was amended with the Controlled Substance Act that added anabolic steroids and prohormones (a precursor to a hormone) to the list of controlled substances and makes possession of the substances a federal crime. Still, some athletes continue to use them illegally despite evidence that using them this way can cause many serious health problems.

Anabolic steroids are testosterone derivatives that help the body metabolize ingested proteins and facilitate the synthesis of skeletal muscle. They also delay fatigue and may create a feeling of euphoria.

DHEA supplements were taken off the U.S. market in 1985 and made available only by prescription. DHEA was then reintroduced as a nutritional supplement in 1994 after the passing of the Dietary Supplement Health and Education Act . DHEA is still considered a banned substance by many sports organizations and athletes are cautioned about its use.

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Encyclopedia of Sports Medicine and Science Contents · Search · Homepage ANABOLIC STEROIDS: Side Effects Harm Kuipers, M.D., Ph.D.
Department of Physiology
University of Limburg
P.O. Box 616
6200MD Maastricht
The Netherlands

Kuipers, H. (1998). Anabolic steroids: side effects. In: Encyclopedia of Sports Medicine and Science, T.D.Fahey (Editor). Internet Society for Sport Science: http://sportsci.org. 7 March 1998.

Liver Function
Anabolic Steroids and the Male Reproductive System
Anabolic Steroids and the Female Reproductive System
Serum Lipoproteins and the Cardiovascular System
Psychological Effects
Additional Side Effects
References

Benign (adenoma's) and malign tumors (hepatocellular carcinoma) have been reported. There are rather strong indications that tumors of the liver are caused when the anabolic steroids contain a 17-alpha-alkyl group. Usually, the tumors are benign adenoma's, that reverse after stopping with steroid administration. However, there are some indications that administration of anabolic steroids in athletes may lead to hepatic carcinoma. Often these abnormalities remain asymptomatic, since peliosis hepatis and liver tumors do not always result in abnormalities in the blood variables that are generally used to measure liver function.

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What are steroids?  Steroids are drugs that mimic certain natural hormones in the body that regulate and control how the body works and develops. There are two main groups of natural steroids - anabolic steroids and corticosteroids. It is the anabolic steroids that tend to be misused, mainly because they are similar to the male hormone testosterone and they can improve endurance and performance and stimulate muscle growth. 

Some people take the anabolic steroids to help build muscles or to try and look more ‘manly’. Other people take them to improve how they perform at sports, such as sprinting and cycling.

They’re used by some bodybuilders, athletes and other sports people because of the performance enhancing effects, and these users may consume 10-100 times the medical dose. Some younger people use them to try and look more attractive, despite risking the negative effects on their looks.

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Anabolic steroids are a class of steroid hormones based on the androgen testosterone . Anabolic steroids are also known as anabolic-androgenic steroids or AAS or performance enhancing drugs .

Anabolic steroids increase the rate of protein synthesis within cells. The building of cellular tissue (anabolism) is especially noticeable in muscles. Anabolic steroids also have androgenic and virilizing effects. They influence masculine characteristics such as the growth of the vocal cords and body hair.

Anabolic steroids have been attractive to athletes and bodybuilders because they increase the size and strength of muscles. They also increase aggressiveness and competitiveness, which can be desirable traits in sports. Anabolic steroids may be prescribed to promote appetite, stimulate bone growth, induce male puberty, to lessen the effects of muscle wasting from chronic diseases, such as cancer or AIDS, and may show promise as a male contraceptive.

Anabolic steroids change muscle mass and strength by two processes. First, the steroids lead to an increased production of proteins, which are the building blocks of muscle. The steroids also block the effect of the hormone cortisol on muscle tissue, so that existing muscle is broken down at a slower rate. Additionally, anabolic steroids lead to cells differentiating into muscle more readily than fat.

The largest and most trusted provider of Anabolic Steroids information. Featuring over 1 million pages and a massive steroids community.

" Anabolic steroids " is the familiar name for synthetic substances related to the male sex hormones (e.g., testosterone). They promote the growth of skeletal muscle ...

How do anabolic steroids affect the brain? Anabolic steroids work differently from other drugs of abuse; they do not have the same short-term effects on the brain.

Anabolic Steroids : From The Beginning Years. At present time, there are several anabolic steroid derivatives that are available to us. We can enjoy a varied range of ...

This medicine belongs to the group of medicines known as anabolic steroids. They are related to testosterone, a male sex hormone. Anabolic steroids help to rebuild tissues that have become weak because of serious injury or illness. A diet high in proteins and calories is necessary with anabolic steroid treatment.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, anabolic steroids may be used in certain patients with the following medical conditions:

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This medicine belongs to the group of medicines known as anabolic steroids. They are related to testosterone, a male sex hormone. Anabolic steroids help to rebuild tissues that have become weak because of serious injury or illness. A diet high in proteins and calories is necessary with anabolic steroid treatment.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, anabolic steroids may be used in certain patients with the following medical conditions: